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Dermáme

Squalane Oil for Youthfull Skin ₹ 994.00
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Glowing healthy skin is everyone’s dream. Having a healthy skin regime that you follow religiously will not only leave you feeling fresh but will also keep your skin young and soft. Exceptional care is just not enough for healthy supple skin; using the right ingredients is what is going to get you there. And that should be though investing in the right kind of skin care products.

In today’s world, our skin is constantly exposed to harsh weather conditions and to find a product that helps tackle all your problems is very difficult. Right? Well, not anymore!

Dermáme is an authentic Squalane skin care product, where in the ancient beauty regime - involving squalane that had been kept a secret for generations, is brought to the customer after pain-staking research and purification. Squalane is a skin-loving agent that leaves the skin feeling rejuvenated and helps smoothen the skin by replenishing surface skin lipids. It is an excellent moisturizer that fosters anti-aging effects and regenerates skin from within. Dermáme is the first ever brand in India bringing to you the goodness of squalane that will not only leave your skin feeling younger, healthier and glowing but will also help keep your skin hydrated.

  Flora by Dermáme is packed with the goodness of squalane that is extracted from olives. Flora houses 92% to 94% pure squalane that is then combined with ingredients devoted to gifting you with beautiful nourished skin. Introducing Flora into you daily regime will reap results in just around 15 days!
  Fauna by Dermáme is filled with the richness of squalane that is extracted from shark liver. Squalane in Fauna is 99% pure and has higher activity than the squalane extracted from olives. This means healthy beautiful skin is now achievable in as quick as 10 days.
 
Why Squalene?
Squalene is critical in reducing free radical oxidative damage that is caused to the skin because of its exposure to harsh conditions. This natural chemical is produced in the human body in two ways: partly from endogenous cholesterol synthesis and partly from dietary sources, especially in populations consuming large amounts of olive oil and shark oil. The endogenous synthesis of squalene begins with the production of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA). The initial reduction of HMG CoA (aniacin‑dependent reaction) results in the formation of mevalonate.
 
What is Squalene?
Squalene (C30H50) is a structurally unique triterpene compound that is one of the main components (about 13%) of skin surface lipids. Squalene being the main component of the skin surface polyunsaturated lipids, acts as an antioxidant, emollient and hydrating agent for the skin. It also aids in the skin’s anti-tumor activities. Scientists discovered that in the beginning of life on Earth, microbes and later in the Precambrian period membrane cells of organisms were full of squalene. At the time, the substance was essential for survival as the organisms had to thrive in a hostile environment that lacked oxygen. It was only recently discovered that this natural chemical component is present in small amounts in the human body too. Newborns show the highest amount of squalene in their blood with this amount rapidly decreasing over the years. This concentration of squalene in the blood drops drastically between the ages of 30 and 40.
How is Squalene good for the skin?
At the beginning of the 1950s it was found that squalene forms an important component in sebum and its role is skin hydration, repairing of damaged skin and skin rejuvenation was justified. Small glands known as the sebaceous glands produce the oily matter known as sebum that is produced in the hair follicles to help lubricate the skin. It is transported in the blood by the small and very small density lipoproteins. This sebum is found in the greatest amount on the face & scalp and squalene is one of the predominant components in it. The utmost squalene concentration in human is seen in skin lipids, about 500 μg/g, and in the adipose tissue, 300 μg/g. Squalene is known to protect the skin surface by preventing lipid peroxidation that is caused due to exposure to UV light. Squalene isn’t steady enough for be used in products meant for shelf lives. Hence squalane is used instead; derived from squalene, and is the more stable form of this molecule, as well as being colorless and odorless. Thus all our products contain squalane.
Why use Dermáme?

Emollient:
Squalane is easily absorbed deep into the skin leaving the skin supple and flexible without any greasy residue left behind. Cosmetic studies with biometric molecules investigated with experimental designs in order to study the optimal composition of a squalene mixture in an oil-in-water emulsion, showed results that the viscosity and stability of the emulsions were the greatest influence on the percentage of squalane. Thus makes it a suitable component for cosmetic products.

Anti Aging Properties:
According to the February 2010 issue of the SOFW-Journal, squalene’s hydrating and skin-softening effects helps in reducing the appearance of fine lines and wrinkles, thus helping maintain healthy, glowing skin.

Protection against UV Rays:
According to a study conducted by K. Ohsawa, et al., published in the May 1984, they found that squalene protects skin from damage caused due to UV radiation. Squalene extracted from shark oil can have an odor and thus 




it is purified further for more stability. Thus prescription acne creams such as Adapalene and cosmetic companies use squalane in sunblock creams.

Skin Hydration:
Occlusion leads to increased skin hydration, as there is less water loss. That being the case, Rissmann et al. revealed that a vernix caseosa (VC) should be an innovation barrier for those with skin that lacks it. This is because vernix caseosa facilitates stratum corneum hydration. For this purpose a study was conducted wherein several lipid fractions were isolated from lanolin and were subsequently mixed with squalene, ceramides, triglycerides, cholesterol, and fatty acids to generate semi-synthetic lipid mixtures close to VC. The research showed promising results with increased rate of barrier recovery. Okuda et al. also found that in skin treated in 5% sodium lauryl sulfate, the elevated levels of trans-epidermal water loss (TEWL) and riboflavin penetration were reversed by squalene supplementation. According to the MedLibrary.org, Squalene has humectant properties that increase the water retention capacity of the skin, thus leaving the skin soft and supple.



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